Studies on Synthetic Sweetening Agents. III

SuperSweet—a resource on natural and artificial sweetening agents

A vast number of sweet tasting molecules are known, encompassing small compounds, carbohydrates, d-amino acids and large proteins. Carbohydrates play a particularly big role in human diet. The replacement of sugars in food with artificial sweeteners is common and is a general approach to prevent cavities, obesity and associated diseases such as diabetes and hyperlipidemia. Knowledge about the m...

Amines as gas sweetening agents Master thesis Submitted

Tetrametallic lanthanide(III) phosphonate cages: synthetic, structural and magnetic studies.

The synthesis, structures and magnetic properties of a family of lanthanide complexes containing phosphonate ligands are reported. Reaction of hydrated lanthanide nitrate and (t)butylphosphonic acid under reflux conditions in iso-butanol, in the presence of pivalic acid as a co-ligand produced five new lanthanide complexes; pyridine (py) was present as a base. The compounds formed are tetrameta...

Molecular docking studies on xanthohumol derivatives as novel ‎anticancer agents ‎

A set of Xanthohumol derivatives were selected and molecular docking studies of these ‎compounds on thioredoxin reductase were conducted. Based on new structural patterns using in ‎silico-screening study, new potent lead compounds were designed. The results due to validated ‎docking protocols lead to find that Thr58, Gly57, Gly21, Asp334, Glu163, Ala130, IIe332, ‎Val44 and Gly132 are the main a...

Studies on Synthetic and Natural Melanin and Its Affinity for Fe(III) Ion

In this work, we measured the metal-binding sites of natural and synthetic dihydroxyindole (DHI) melanins and their respective interactions with Fe(III) ions. Besides the two acid groups detected for the DHI system: catechol (Cat) and quinone-imine (QI), acetate groups were detected in the natural oligomer by potentiometric titrations. At acidic pH values, Fe(III) complexation with synthetic me...